There may be several reasons for this behavior:

• Your screen resolution or Windows theme has changed since the last time the hot spot set was used.
• The plug-in window may be covered by one or more windows (use control+tab to inspect all opened windows and close the ones that are no longer needed).
• The plug-in may be using floating windows which means that they do not stay in the same place.

For other troubleshooting tips and tricks, please see the user manual that comes with the Hot Spot Clicker scripts.